hrp0094p2-149 | Diabetes and insulin | ESPE2021

Assessment of the percentage of T lymphocytes and B lymphocytes with the expression of selected activation markers in patients with type 1 diabetes mellitus depending on the presence of antibodies against EBV antigens.

Rysz Izabela , Hymos Anna , Klatka Maria ,

Introduction: After contact with the antigen, lymphocytes require activation for proliferation and differentiation into effector cells. Activation of lymphocytes results in the expression of activation markers. The CD69 antigen appears first on the surface of lymphocytes. This occurs one hour after receiving the activation signal. The CD69 molecule acts as a cellular stimulating signal, causing further activation and proliferation of cells, stimulating the syn...